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Gene Wilder, star of movies such as Blazing Saddles, Willy Wonka and the Chocolate Factory and Stir Crazy has died aged 83.

Wilder’s nephew said that the actor died of complications from Alzheimer’s disease at his home in Stamford, Connecticut on Monday.

Wilder, whose third wife Gilda Radner died of ovarian cancer, was treated for lymphoma in 2000.

On Monday, former colleague Mel Brooks tweeted: “Gene Wilder-One of the truly great talents of our time. He blessed every film we did with his magic & he blessed me with his friendship.”